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???? ????3??13?????GEN??????·?????????????????????г???2018???????????15????????????????“????????”??????4??????????????????????3?????
 
2018??????????Top 15
 
????K????????Top 5
 
????????????????????????????Humira????????GEN??2013??????????????????????“???”???????????2013??????????????106.59?????????2018???199.36???????????87%??
 
????15???????????????У???10?????????????????????6??????????λ??????????????????????PD-1??????Keytruda??????????88.3%????????????Keytruda?????????????????????壬???????????????
 
????????PD-??L??1??????????????????????????Keytruda???????????????????????г????????????????λ????2018???????????????γ??Opdivo??
 
????Keytruda?????????FDA?????16????????????11??????????????Keytruda?????????????????????5???????????8???????????????????????FDA?????Keytruda??????????????????????????????г?????????????????Keytruda???????г?????????????????????
 
??????????????????????????????????????????λ???????6???????????У??5??????о???3?????????????????????????????????2017???4???????5?????????Janssen??????????????Stelara????????????λ?а?????????
 
????Stelara????????????????????????????????????????????????12??IL-12????????????23??IL-23????Stelara??2009?????У???????????????????????????м??????м?????????????????CD????EvaluatePharma?????2024??Stelara????????????64.66???????
 
??????????Stelara???????????????????????????2019??????????????AAD?????????????Novartis????????????????Cosentyx??secukinumab??????????????о?CLARITY????????????о????ж????????????м??????????п??????Cosentyx??Stelara????????????????????????Щ??????????QoL?????棬Cosentyx????????????Stelara??????????????2018??????CLARITY?о?????????????????12????16???Cosentyx??Stelara????Ч??????????????????
 
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????????GEN?????????2017??????????Top 15????????????????????Lantus??????????????????Neulasta??????????????
 
???????????????????Ч???????????????????????????г???????2014????84.3???????????????????????????????????????2015??2???5??????2015??12???????????????????????Basaglar??????????????????????????????????????????????????????????г?????????????????????????
 
??????????????Neulasta?????“????”??????????????????????????????????????????Neulasta????????????????????2017??Neulasta???????????45.6???????????87%????????????????г???Neulasta?????????????2015??6???????????????2017??8??????2018??FDA?????????????????????????Fulphila??
 
????5??????????????
 
???????????????????15?????????????5???????????????????????????????????????????????????????????????????????????????У????????????Remicade?????????????2017???????????17.4%??
 
????Remicade??????????????????????????????????????????????????????????1998??????????????С?
 
????2016??Celltrion?????????????????Inflectra???????????????????????????????3??????????????????????????Remicade????????????????????????Remicade????г?????-10%????????????????????
(2019/4/15 15:18:13  ???????    ???5985??)

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